Troponin assays are not merely a lot more delicate but are also additional certain than CK-MB assays. Expression of CK-MB is not distinctive to the guts.37 CK-MB is located in skeletal muscle and the gastrointestinal tract in addition to within the uterus of pregnant Ladies.38 What's more, in patients with myopathies, the CK-MB information of skeletal muscle mass can raise markedly to approximately fifty% of the entire amount for each gram of tissue.
There's an association concerning increased troponin concentrations and remaining ventricular hypertrophy.195 It is thought which the subendocardium might have impaired perfusion as a result of elevated wall tension, concomitant endothelial dysfunction and, generally, amplified myocardial oxygen need.
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